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For twitch I recommend: 9x Attack Damage Marks, 2x Attack Speed quints, 1x Attack damage Quint, 4 Armor Yellow and 5 Health Yellow, 9 MR glyphs
Masteries: 21/9/0
Build Berseker/Botrk/Phantom Dancer/Last Whisper / Infinity Edge/ Defensive item
The most important things: learn to farm and not miss creeps, learn to position and kite your ennemies.
If you are ahead use the catch combo: stealth into an isolated ennemy: use your Z to slow, auto attack, use BOTRK active if they keep running, use E when you reach max stacks and they should be dead.
In team fight stay at backline and use your ult to kill ennemy team from a safe distance.
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