After installing Python, the security settings for C:\Python27 may be inherited from the root (C:\). This could be an issue depending on how Windows was installed on your system. You can open computer, open C:\ partition, right click on Python27, properties, security, advanced, and then change setting to not inherited and the owner to Administrators or your account, then go back and set full control if its not already set.
I noticed I was getting an error with the ez_install.py script if I didn't fix the security settings, but despite the error (access denied), it still seemed to work, but I wasn't sure if there would be issues later.
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