You're running S4 under VMWare and Xigncode/Themida don't complain?
Yes I actually comment the priority line in my scripts because in my experience anything that wasn't the default one performed worse, but maybe I thought it was just me so I left it in the topic. I'll follow your suggestion and put both on High. You should post that stuff in the topic itself as a contribution sir.
If the high precision sleep I have included among the optimizations doesn't help you, then you should check RHCP's topic (a great AHK contributor) for alternatives, that's where I took the "sleepz" function from: