Could also be a hardware clash...
But most likely overheating.
What I duggest is open up your PC box and just check the area around your CPU. Look for these things:
Bad Things:
-No Cpu Fan
-No Heatsink
-No Heatgel (Lift up your CPU fan and you should see a little pad or a gel)
*If you see what looks to be like a gel was there (crusty stuff) then your Heatsink is not working well. To fix this disconnect you PC from the wall and take your cpu fan/heatsink block off and wipe it clean. Then go buy some heat gel from your local PC store (2-10 bucks) and get bank card or a licence or whatever, smear some gelm on the top of your CPU with your finger, making sure theres no air bubbles and it about 1mill thick, then get your card and wipe all the excess off (about 1/2 of a mill gel is what you want). If there is too much gel it wont transfer heat at all and cause more trouble, if theres not enough it will dry up and youll have to do it again.
Also, if your CPU area is dusty clean it best as you can (without liquids, Duh!) as dust traps the heat.
Also try leaving the side of your tower off and try running 3 clients again. And post what happens.
If you dont have to heatsink, get one, same goes for a CPU fan.
Good things:
-CPU fan
-Heatsink
-Heatgel
-Good ventilation (Make sure all opening to the tower are open and clean, if no air can get in or out it will basically turn into a heater.)
There should be 2 holes in the back of the tower (On a vertical standing unit) one toward the bottom of the case and one higer on the case (or actually through the top) the top hole should be blowing out essentually taking cold air from the bottom.
Ok well thats all I can think of as of now, do some tests and report back.
*You may also want to go into task manager (Ctrl + Alt + Del) and goto the processes tab and close everything that you know on that list thart your not using)
Anyways, goodluck
Hojo