[C# Question] DataTable vs. Direct-Access

[Belth]

The public release of COEmu v2 reads/writes/updates data in a MySQL database directly. I'd like to know what are the disadvantages of manipulating that data in a DataTable (rather than doing it directly) and then transferring it to the MySQL database.

A glaring problem could be that if the programme for whatever reason closes then more data would be lost. Periodic transfers would be done to minimize this lost.

Any other problems/suggestions are welcomed.