A nice combination of two skills that I have found is Sabotage+impact. Sabotage is such a great skill, especially if you have high speed or tornado of blows talent - or a weapon that multi-hits often. Coupled with impact (and Thief skill would be nice here aswell) this can be devastating at lower levels where people don't have 8+ weapons.
Here is my example - has martial arts so when we both are out of weapons, I can win in hand to hand combat