One isn't inherently safer, and blanket statements like "DMA is safer" isn't true.
It depends on the developer and quality of the product the developer actually puts out.
For example if I knew that a certain dev couldn't bypass Battleye (Tarkov's AC) without hardware, I wouldn't buy anything from them at all.
Overall I would ignore whether it's DMA or not, ignore the user count, etc.
You never really know what you're buying, so the best way to determine if a cheat is safe or not is to look at the last time they've been detected, and how often they get detected.
That would be my sole factor on choosing a cheat or not.